441171
(Bromomethyl)cyclobutane
97%
Synonyme(s) :
Cyclobutylmethyl bromide
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
About This Item
Produits recommandés
Niveau de qualité
Pureté
97%
Forme
liquid
Indice de réfraction
n20/D 1.48 (lit.)
Point d'ébullition
123-124 °C (lit.)
Densité
1.326 g/mL at 25 °C (lit.)
Chaîne SMILES
BrCC1CCC1
InChI
1S/C5H9Br/c6-4-5-2-1-3-5/h5H,1-4H2
Clé InChI
FLHFTXCMKFVKRP-UHFFFAOYSA-N
Catégories apparentées
Description générale
(Bromomethyl)cyclobutane (bromomethyl-cyclobutane) is an aryl fluorinated building block. Its reaction with various hydroxychromen-4-one derivatives in the presence of anhydrous K2CO3/dry acetone and Bu4N+I- (PTC) has been investigated.
Application
(Bromomethyl)cyclobutane may be used in the synthesis of racemic 3-cyclobutylalanine and 17-(cyclobutylmethyl)morphinan-3-ol (butorphan).
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Flam. Liq. 3
Code de la classe de stockage
3 - Flammable liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
105.8 °F - closed cup
Point d'éclair (°C)
41 °C - closed cup
Équipement de protection individuelle
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Photochemical synthesis and antimicrobial studies of new chromen-4-one based vinyl ethers.
Arabian Journal of Chemistry (2013)
Journal of medicinal chemistry, 53(1), 402-418 (2009-11-26)
The phenolic group of the potent mu and kappa opioid morphinan agonist/antagonists cyclorphan and butorphan was replaced by phenylamino and benzylamino groups including compounds with para-substituents in the benzene ring. These compounds are highly potent mu and kappa ligands, e.g.
Journal of medicinal chemistry, 52(19), 6163-6167 (2009-09-15)
The natural proteasome inhibitor salinosporamide A from the marine bacterium Salinispora tropica is a promising drug candidate for the treatment of multiple myeloma and mantle cell lymphoma. Using a comprehensive approach that combined chemical synthesis with metabolic engineering, we generated
Journal of medicinal chemistry, 47(1), 165-174 (2003-12-30)
A series of 10-ketomorphinan analogues were synthesized, and their binding affinity at all three opioid receptors was investigated. In most cases, high affinity at micro and kappa receptors, and lower affinity at delta receptor was observed, resulting in good selectivity
Cyclopropylmethyl-and cyclobutylmethyllithium by an arene-catalyzed lithiation. Stability and reactivity.
Tetrahedron, 66(16), 2928-2935 (2010)
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique