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Key Documents

384127

Sigma-Aldrich

Diphenyl ditelluride

98%

Synonyme(s) :

Phenyl ditelluride

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About This Item

Formule linéaire :
(C6H5)2Te2
Numéro CAS:
Poids moléculaire :
409.41
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Pureté

98%

Forme

powder

Pf

65-67 °C (lit.)

Chaîne SMILES 

[Te]([Te]c1ccccc1)c2ccccc2

InChI

1S/C12H10Te2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H

Clé InChI

VRLFOXMNTSYGMX-UHFFFAOYSA-N

Description générale

Diphenyl ditelluride (PhTe)2 is a versatile reagent used in the organic synthesis. Neurotoxicity by (PhTe)2 depends on the modulation of signaling pathways initiated at the plasma membrane. Comparative toxicological effects of diphenyl diselenide and (PhTe)2 in mice after in vivo administration has been reported. Teratogenic effects of (PhTe)2 on chicken embryo development has been investigated. The oxidative addition of (PhTe)2 to [Pd(PPh3)4] in dichloromethane is reported to yield [Pd6Cl2Te4(TePh)2(PPh3)6]·1/2CH2Cl2.

Application

Diphenyl ditelluride may be used in the assay of organolithium and Grignard reagents.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Consulter la Bibliothèque de documents

Daiane Francine Meinerz et al.
PeerJ, 2, e290-e290 (2014-04-09)
Organoselenium compounds have been pointed out as therapeutic agents. In contrast, the potential therapeutic aspects of tellurides have not yet been demonstrated. The present study evaluated the comparative toxicological effects of diphenyl diselenide (PhSe)2 and diphenyl ditelluride (PhTe)2 in mice
Robert B Cody et al.
Journal of the American Society for Mass Spectrometry, 30(7), 1321-1324 (2019-05-08)
Elemental compositions are commonly determined from the exact m/z of the monoisotopic peak, which is often the lightest isotope. However, the lightest isotope peak is often weak or absent and the monoisotopic peak can be difficult to identify for organometallics
Regina Pessoa-Pureur et al.
Oxidative medicine and cellular longevity, 2014, 458601-458601 (2014-07-23)
Evidence from our group supports that diphenyl ditelluride (PhTe)2 neurotoxicity depends on modulation of signaling pathways initiated at the plasma membrane. The (PhTe)2-evoked signal is transduced downstream of voltage-dependent Ca(2+) channels (VDCC), N-methyl-D-aspartate receptors (NMDA), or metabotropic glutamate receptors activation
Bruna Comparsi et al.
Toxicology mechanisms and methods, 24(8), 529-535 (2014-05-28)
Diphenyl ditelluride (PhTe)₂ is a versatile molecule used in the organic synthesis and it is a potential prototype for the development of novel biologically active molecules. The mechanism(s) involved in (PhTe)₂ toxicity is(are) elusive, but thiol oxidation of critical proteins
Carlos André Prauchner et al.
Toxicology mechanisms and methods, 23(9), 660-664 (2013-08-15)
Studies of our group has demonstrated that (PhSe)2 plays some pharmacologic activities. In addition, it is possible that this compound would be an alternative source of organic selenium in animal foods. However, previous works showed that diphenyl diselenide (PhSe)2 and

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