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Key Documents

343862

Sigma-Aldrich

1-Bromoheptadecafluorooctane

99%

Synonyme(s) :

Heptadecafluorooctyl bromide, Perfluorooctyl bromide

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About This Item

Formule linéaire :
CF3(CF2)7Br
Numéro CAS:
Poids moléculaire :
498.96
Numéro Beilstein :
2016022
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22

Pureté

99%

Forme

liquid

Indice de réfraction

n20/D 1.305 (lit.)

Point d'ébullition

142 °C (lit.)

Densité

1.93 g/mL at 25 °C (lit.)

Chaîne SMILES 

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br

InChI

1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26

Clé InChI

WTWWXOGTJWMJHI-UHFFFAOYSA-N

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Description générale

1-Bromoheptadecafluorooctane (perfluorooctyl bromide) is a perfluorocarbon. Poly(ethylene glycol)ylated polyester nanocapsules of perfluorooctyl bromide were surface-decorated with a RGD (arginine-glycine-aspartic acid) peptide, were used for tumor imaging. Nanocapsules of perfluorooctyl bromide have been developed as dual contrast agent for ultrasonography and Magnetic Resonance Imaging (MRI).

Application

1-Bromoheptadecafluorooctane (perfluorooctyl bromide) can be used as contrast agent in the vascular system for fluorine-19 magnetic resonance imaging or as synthetic oxygen carrier. It was also employed as oxygen carrier in the emulsions used as blood substitutes.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Molecular imaging with magnetic resonance imaging (MRI) targeted contrast agents has emerged as a promising diagnostic approach in cancer research to detect associated biomarkers. In this work, the potential of (19)F MRI was investigated to detect angiogenesis with α(ν)β(3)-targeted perfluorooctylbromide
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Perfluoro-octyl bromide (PFOB), one of the perfluorochemical oxygen transporters, improved postischemic cardiac dysfunctions. Also norepinephrine (NE) is one of the important inducible factors on reperfusion arrhythmias (ventricular fibrillation [VF]). We used these methods to evaluate the relationship between PFOB emulsion
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Acta radiologica (Stockholm, Sweden : 1987), 54(3), 278-283 (2013-01-16)
Multimodal contrast agents usually containing two or more signal components can be used for several imaging modalities. Thus, complimentary information can be obtained by using just one kind of contrast agents. To investigate the potential of superparamagnetic perfluorooctylbromide nanoparticles (M-PFOBNP)
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