247383

Boron tribromide dimethyl sulfide complex solution

1.0 M in methylene chloride

• Synonyme(s) : Dimethyl sulfide-tribromoborane, Tribromoborane-methyl sulfide
• Formule linéaire : (CH₃)₂S·BBr₃
• Numéro CAS: 29957-59-3
• Poids moléculaire : 312.66
• Numéro MDL: MFCD00043296
• Code UNSPSC : 12352101
• ID de substance PubChem : 24854866
• Nomenclature NACRES : NA.22

Propriétés

• Forme: liquid
• Niveau de qualité: 100
• Concentration: 1.0 M in methylene chloride
• Densité: 1.456 g/mL at 25 °C
• Chaîne SMILES: C[S+](C)[B-](Br)(Br)Br
• InChI: 1S/C2H6BBr3S/c1-7(2)3(4,5)6/h1-2H3
• Clé InChI: NCVLHAUANAMSTL-UHFFFAOYSA-N

Description

Application

Boron tribromide dimethyl sulfide complex (BBr₃S(CH₃)₂) can be used as a reagent:

• To prepare demethylated products from aryl methyl ethers by deprotection of methyl groups.
• To hydrolyze 1,3-methylenedioxole ring compounds to 1,2-dihydroxy compounds.
• To prepare benzyl S,S′-diphenyl acetal by reacting with phenylacetic acid and thexylphenylthioborane.
• To synthesize Baylis−Hillman adducts and α-halomethyl enones by the reaction between aldehydes and 3-buten-2-one.

Reactant for preparation of:

• Precursor of HIV protease inhibitor KNI 764 using cation-exchange resin mediated Mannich reaction

Reagent for:

• Baylis-Hillman reactions

Informations sur la sécurité

• Pictogrammes: GHS08,GHS05,GHS07
• Mention d'avertissement: Danger
• Mentions de danger: H314,H336,H351
• Conseils de prudence: P202 - P261 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• Organes cibles: Central nervous system
• Risques supp: EUH014
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable