201634

6-Aminofluorescein

• Synonyme(s) : Fluoresceinamine isomer II
• Formule empirique (notation de Hill): C₂₀H₁₃NO₅
• Numéro CAS: 51649-83-3
• Poids moléculaire : 347.32
• Numéro Beilstein : 51708
• Numéro CE : 257-334-7
• Numéro MDL: MFCD00005051
• Code UNSPSC : 12171500
• ID de substance PubChem : 24852016
• Nomenclature NACRES : NA.47

Propriétés

• Forme: powder
• Pf: 285 °C (dec.) (lit.)
• Solubilité: methanol: 1 mg/mL, clear, yellow to very dark yellow-orange
• λmax: 495 nm
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: Nc1ccc2C(=O)OC3(c4ccc(O)cc4Oc5cc(O)ccc35)c2c1
• InChI: 1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2
• Clé InChI: YOAWSYSKQHLFPM-UHFFFAOYSA-N

Description

Application

6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed ‘buckysomes′. 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein.

6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).

Autres remarques

Note: Do not confuse with fluorescamine.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves