GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Synonymes:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Espèce(s):
Human GRIN2B (2904), Mouse Grin2b (14812), Rat Grin2b (24410), chicken GRIN2B (417965), dog GRIN2B (494009), domestic cat GRIN2B (101094356), Horse GRIN2B (100063746), cow GRIN2B (537804), domestic guinea pig Grin2b (100731840), naked mole-rat Grin2b (101723091)
ID UniProtKB:
ID du gène:
- Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
- Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
- Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
- sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Small Molecule - Allosteric Modulator
Référence du produit
Description
Espèce(s)
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espèce(s)
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Espèce(s)
human
Small Molecule - Antagonist
Antibodies
Référence du produit
Description
Espèces réactives
Application
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Rabbit pAb, liquid, Calbiochem®,
Espèces réactives
rat
Application
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-NMDAR2B Antibody, clone 5C18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
bovine, canine, feline, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-GRIN2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Référence du produit
Description
Espèce(s)
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human
Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
human