928925

Poly(ethylene glycol)-block-poly(2-(Dimethylamino)ethyl methacrylate)

quaternized, PEG average M_n 5,000, quaternized PDMAEMA M_n 18,000

• Synonym(s): PEG-PQDMAEMA, Quaternized PEG-PDMAEMA
• Linear Formula: CH₃(C₂H₄O)_nC₆H₇O₂N(C₉H₁₈O₂NCl)_mC₇H₅S₂
• UNSPSC Code: 51171641
• NACRES: NA.25

Properties

• Quality Level: 100
• form: powder
• mol wt: PEG average M_n 5,000
• color: white to pink

Description

General description

Poly(ethylene glycol)-block-Poly(2-(Dimethylamino)ethyl methacrylate) quaternized (PEG-b-PQDMAEMA) is a biocompatible block polyelectrolyte composed of a neutral PEG block and a cationic quaternized Poly(2-(Dimethylamino)ethyl methacrylate) (PDMAEMA) block. The PQDMAEMA carries quaternary ammonium salt moieties along the polymer chain.

Application

• Antimicrobial applications
• Non-viral gene delivery
  
  PEG-b-PQDMAEMA is a versatile polymer with applications in antimicrobial applications and gene delivery. Due to its high efficacy in antimicrobial systems, it is an ideal candidate for the fabrication of long-lasting, contact-active bactericidal materials. PQDMAEMA is also a promising material for non-viral gene delivery. PEGylation of PQDMAEMA reduces cytotoxicity and increases gene delivery efficiency.
  

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3