234907

2-(Dimethylamino)ethyl methacrylate

contains 700-1000 ppm monomethyl ether hydroquinone as inhibitor, 98%

• Synonym(s): Methacrylic acid 2-(dimethylamino)ethyl ester
• Linear Formula: CH₂=C(CH₃)COOCH₂CH₂N(CH₃)₂
• CAS Number: 2867-47-2
• Molecular Weight: 157.21
• Beilstein: 1757048
• MDL number: MFCD00008589
• UNSPSC Code: 12162002
• PubChem Substance ID: 24854063
• NACRES: NA.23

Properties

• vapor density: 5.4 (vs air)
• vapor pressure: <1 mmHg ( 25 °C)
• Assay: 98%
• form: liquid
• contains: 700-1000 ppm monomethyl ether hydroquinone as inhibitor
• refractive index: n20/D 1.439 (lit.)
• bp: 182-192 °C (lit.)
• density: 0.933 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CN(C)CCOC(=O)C(C)=C
• InChI: 1S/C8H15NO2/c1-7(2)8(10)11-6-5-9(3)4/h1,5-6H2,2-4H3
• InChI key: JKNCOURZONDCGV-UHFFFAOYSA-N

Description

General description

2-(Dimethylamino)ethyl methacrylate (DMAEMA) is a methacrylic acid derivative that is used as a monomer in the production of polymers with a wide range of applications. The most common use of DMAEMA is in the production of cationic polymers, which are highly charged and have applications such as flocculants, coagulants, dispersants, and stabilizers. In addition, DMAEMA-based polymers have found uses in drug delivery systems, tissue engineering, and gene therapy, owing to their excellent biocompatibility and biodegradability properties. DMAEMA can also be used as a modifying agent in coatings, adhesives, and textiles to improve properties such as adhesion, hardness, and water resistance.

Application

2-(Dimethylamino)ethyl methacrylate (DMAEMA) can be used as starting material in the synthesis of poly (DMAEMA) and amphiphilic block copolymers. Poly (DMAEMA) is a thermal and pH-sensitive biocompatible polymer widely used in the following applications.

• Quaternized poly (DMAEMA) can be used to prepare highly efficient antibacterial magnetic particles. The high density of quaternary ammonium groups generated via surface-initiated ATRP are responsible for high antibacterial activity.
• Ag nanoparticles immobilized into a poly (DMAEMA) brush layer can be used as a sensor platform for the detection of organic molecules by surface-enhanced Raman spectroscopy (SERS).
• It can also be used to prepare stable polymer-based gene delivery systems.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H302 + H312,H314,H317
• Precautionary Statements: P261 - P272 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point(F): 147.2 °F - closed cup
• Flash Point(C): 64 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves