V900429
N-Acetyl-L-Cystein
98%, Vetec™
Synonym(e):
LNAC, NAC
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Alle Fotos(2)
About This Item
Lineare Formel:
HSCH2CH(NHCOCH3)CO2H
CAS-Nummer:
Molekulargewicht:
163.19
Beilstein:
1724426
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
Empfohlene Produkte
product name
N-Acetyl-L-Cystein, Vetec™, reagent grade, 98%
Qualität
reagent grade
Produktlinie
Vetec™
Assay
98%
Form
powder
Farbe
white to off-white
mp (Schmelzpunkt)
106-108 °C (lit.)
Anwendung(en)
cell analysis
Lagertemp.
2-8°C
SMILES String
CC(=O)N[C@@H](CS)C(O)=O
InChI
1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChIKey
PWKSKIMOESPYIA-BYPYZUCNSA-N
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Anwendung
- Antioxidant Assay Development: N-Acetyl-L-cysteine (NAC) is used in the metabolic activation and assessment of cytotoxicity of gramine mediated by CYP3A, showcasing its importance in biochemical assays that measure oxidative stress, a critical factor in IVD reagent development (Gao et al., 2024).
- Cell Differentiation and NF-κB Inhibition: NAC′s role extends to inducing oxidative stress and inhibiting NF-κB pathways, which is crucial for the differentiation of cells in AML treatment. This application demonstrates NAC′s utility in clinical diagnostic reagents aimed at cancer treatment and research (Silva et al., 2024).
- Liver Injury Alleviation: Highlighting its therapeutic applications, NAC is used in alleviating acetaminophen overdose-induced liver injury, underlining its potential use in clinical settings and importance in developing therapeutic IVD assays (Chen et al., 2024).
- Enhanced Cancer Treatment Efficacy: Employed in combination therapies, NAC is used to treat posterior gastric pseudomyxoma peritonei, offering insights into its role as a biochemical agent that enhances the efficacy of cancer treatments in diagnostic and therapeutic applications (Sun et al., 2024).
- Regulation of Cell Cycle and Autophagy: NAC′s interactions with 1-Methoxyisobrassinin in ovarian cancer cells illustrate its capability to modulate cell cycle regulation, apoptosis, and autophagy, underpinning its significant role in the development of biomarker detection assays and other IVD products (Zigová et al., 2024).
Biochem./physiol. Wirkung
Antioxidans und mukolytisches Agens. Erhöht den zellulären Pool an Radikalfängern. Apoptose verhindernde Wirkung in neuronalen Zellen und Apoptose induzierende Wirkung in glatten Muskelzellen wurde beobachtet. Inhibiert HIV Replikation. Fungiert möglicherweise als Substrat für mikrosomale Glutathion-Transferase.
Rechtliche Hinweise
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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