1604803

Ritonavir

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 1,3-Thiazol-5-ylmethyl-N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)-methyl]-carbamoyl]-amino]-butanoyl]-amino]-1,6-diphenylhexan-2-yl]-carbamat
• Empirische Formel (Hill-System): C₃₇H₄₈N₆O₅S₂
• CAS-Nummer: 155213-67-5
• Molekulargewicht: 720.94
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Biologische Quelle: synthetic
• Qualität: pharmaceutical primary standard
• Agentur: USP
• Dampfdruck: <0.0000001 kPa ( 25 °C)
• API-Familie: ritonavir
• Form: powder
• Verpackung: pkg of 200 mg
• Hersteller/Markenname: USP
• Lagerbedingungen: protect from light
• Farbe: white to tan
• Löslichkeit: acetonitrile: slightly soluble; ethanol: freely soluble; methanol: freely soluble; methylene chloride: freely soluble; water: practically insoluble
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• InChI: 1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
• InChIKey: NCDNCNXCDXHOMX-XGKFQTDJSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

Anwendung

Ritonavir USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard, standard stock, identification, and standard working solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):

• Lopinavir and Ritonavir Tablets
• Ritonavir Tablets
• Ritonavir
• Lopinavir and Ritonavir Oral Solution

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P280 - P301 + P312 + P330
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable