1143008

Kokain -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Benzoylecgonin-methylester -hydrochlorid
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · HCl
• CAS-Nummer: 53-21-4
• Molekulargewicht: 339.81
• MDL-Nummer: MFCD00058119
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329749446
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: cocaine
• Hersteller/Markenname: USP
• Arzneimittelkontrolle: USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1
• InChIKey: PIQVDUKEQYOJNR-VZXSFKIWSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Cocaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cocaine
• Cocaine Hydrochloride
• Cocaine Hydrochloride Tablets for Topical Solution

Biochem./physiol. Wirkung

Hemmt Dopamin-, Noradrenalin- und Serotonin-Transporter mit K_is von jeweils etwa 300 nm, 900 nm und 400 nm. Im Gegensatz zu Amphetaminen hat es keine Auswirkungen auf die Katecholaminausschüttung.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H300 + H330,H336,H361d
• P-Sätze: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable