1067704

Betamethasondipropionat

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Betamethason-17,21-Dipropionat, 9α-Fluor-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion-17,21-dipropionat
• Empirische Formel (Hill-System): C₂₈H₃₇FO₇
• CAS-Nummer: 5593-20-4
• Molekulargewicht: 504.59
• MDL-Nummer: MFCD00133140
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329748933
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: betamethasone
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: [H][C@@]12C[C@H](C)[C@](OC(=O)CCl)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C27H34ClFO7/c1-5-22(33)35-14-21(32)27(36-23(34)13-28)15(2)10-19-18-7-6-16-11-17(30)8-9-24(16,3)26(18,29)20(31)12-25(19,27)4/h8-9,11,15,18-20,31H,5-7,10,12-14H2,1-4H3/t15-,18-,19-,20-,24-,25-,26?,27-/m0/s1
• InChIKey: UOCNBCVPZWLUKX-HOBFILNXSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

• Efficacy in Alopecia Areata Treatment: A study compared the effectiveness of topical betamethasone dipropionate with minoxidil in treating alopecia areata, highlighting its potent anti-inflammatory properties and its role in promoting hair regrowth. This positions betamethasone dipropionate as a key component in dermatological research aimed at understanding and improving treatment modalities for hair loss conditions (Aslam et al., 2024).


• Post-Surgical Pain Management: Research demonstrated the utility of a cocktail containing betamethasone dipropionate in reducing pain and prolonging analgesic effects post-total knee arthroplasty. This study emphasizes the pharmacokinetic benefits of betamethasone dipropionate in clinical pain management, providing valuable insights for ongoing pharmacological innovations (Luo et al., 2024).


• Improvement in Plaque Psoriasis: Betamethasone dipropionate was analyzed for its effectiveness in treating plaque psoriasis when used as part of a calcipotriol/betamethasone aerosol foam. The results underscore its significant role as a glucocorticoid receptor agonist, enhancing therapeutic outcomes for patients with psoriasis, thereby solidifying its place in anti-inflammatory steroid studies and psoriasis treatment compounds (Gerdes et al., 2024).

Biochem./physiol. Wirkung

Betamethason-17,21-dipropionat ist ein Glucocorticoid mit entzündungshemmender und immunsuppressiver Wirkung.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360FD,H373
• P-Sätze: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1B - STOT RE 2
• Zielorgane: Liver,Kidney,Endocrine system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable