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Wichtige Dokumente
T7165
Tyrphostin 23
≥98%
Synonym(e):
(3,4-Dihydroxybenzylidene)malononitrile, RG-50810
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About This Item
Empirische Formel (Hill-System):
C10H6N2O2
CAS-Nummer:
Molekulargewicht:
186.17
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77
Empfohlene Produkte
Biologische Quelle
synthetic (organic)
Qualitätsniveau
Assay
≥98%
Form
powder
Wirksamkeit
35 μM IC50
Löslichkeit
DMSO: soluble 50 mg/mL, clear, yellow to brownish-yellow
Lagertemp.
2-8°C
SMILES String
Oc1ccc(cc1O)\C=C(\C#N)C#N
InChI
1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H
InChIKey
VTJXFTPMFYAJJU-UHFFFAOYSA-N
Angaben zum Gen
human ... CDK2(1017)
Anwendung
Tyrphostin 23 can be used as a tyrosine kinase inhibitor for studying rat ghrelin-induced MAPK stimulation in GH3 cells. Tyrphostin 23 has also been used to analyze its effects on secretoneurin (SN)-induced chemotaxis of neutrophils.
Biochem./physiol. Wirkung
Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Leistungsmerkmale und Vorteile
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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