T6271

Tylosin

powder, suitable for cell culture, BioReagent

• MDL-Nummer: MFCD07783824
• UNSPSC-Code: 12352207
• PubChem Substanz-ID: 24900364
• NACRES: NA.76

Eigenschaften

• product name: Tylosin, powder, BioReagent, suitable for cell culture
• Produktlinie: BioReagent
• Qualitätsniveau: 200
• Form: powder
• Wirksamkeit: ≥800 units/mg tylosin
• Lagerbedingungen: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• Methode(n): cell culture | mammalian: suitable
• Farbe: off-white to yellow
• Löslichkeit: H₂O: ≤50 mg/mL
• Wirkungsspektrum von Antibiotika: Gram-positive bacteria; mycoplasma
• Wirkungsweise: protein synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
• InChI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
• InChIKey: ICVKYYINQHWDLM-KBEWXLTPSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: macrolide

Anwendung

Tylosin is a mcrolide antibiotic commonly used in veterinary medicine. It has been used to study protein synthesis at the 50S ribosome, implant site abscess prevention in cattle, disposition kinetics and Mycoplasma gallisepticumand Mycoplasma meleagridis infections. It is recommended for use in cell culture applications at 8 mg/L.

Biochem./physiol. Wirkung

Mode of Action: Tylosin Tartrate inhibits bacterial protein synthesis by binding to the 50S (L27 protein) ribosome.

Antimicrobial Spectrum: This product acts against gram-positive bacteria and mycoplasma.

Komponenten

Mischung aus Tylosin A, B, C, und D -tartrat.

Vorsicht

Stock solutions should be filter sterilized and stored at 2-8°C. These solutions are stable at 37°C for 3 days.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H317,H334
• P-Sätze: P280 - P302 + P352
• Gefahreneinstufungen: Resp. Sens. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves