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T5699

Sigma-Aldrich

m-3M3FBS

>97% (HPLC)

Synonym(e):

2,4,6-Trimethyl-N-(3-trifluoromethyl-phenyl)-benzenesulfonamide, N-(3-Trifluoromethylphenyl)-2,4,6-trimethylbenzenesulfonamide

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About This Item

Empirische Formel (Hill-System):
C16H16F3NO2S
CAS-Nummer:
200933-14-8
Molekulargewicht:
343.36
MDL-Nummer:
MFCD00095824
UNSPSC-Code:
41106300
PubChem Substanz-ID:
329826829
NACRES:
NA.77

Assay

>97% (HPLC)

Form

powder

Farbe

white

mp (Schmelzpunkt)

114-114.8 °C (lit.)

Löslichkeit

DMSO: >20 mg/mL

SMILES String

Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc2cccc(c2)C(F)(F)F

InChI

1S/C16H16F3NO2S/c1-10-7-11(2)15(12(3)8-10)23(21,22)20-14-6-4-5-13(9-14)16(17,18)19/h4-9,20H,1-3H3

InChIKey

ZIIUUSVHCHPIQD-UHFFFAOYSA-N

Anwendung

m-3M3FBS has been used for MAP kinase assay in 293T cells. It has also been used for intracellular calcium analysis1. Furthermore, it has been used (at a conc. of 1 μM) as a PLC activator for sensitizing TRPA1 in HEK293t cells2.

Biochem./physiol. Wirkung

First known direct activator of phospholipase C (activates β2, β3, γ1, γ2, δ1 isoforms).

Angaben zur Herstellung

m-3M3FBS is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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