T5639

Ticarcillin Dinatriumsalz

• Synonym(e): (2S,5R,6R)-6-[[(2R)-Carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt
• Empirische Formel (Hill-System): C₁₅H₁₄N₂Na₂O₆S₂
• CAS-Nummer: 4697-14-7
• Molekulargewicht: 428.39
• MDL-Nummer: MFCD07787410
• UNSPSC-Code: 51282427
• PubChem Substanz-ID: 24900306
• NACRES: NA.85

Eigenschaften

• Biologische Quelle: semisynthetic
• Qualitätsniveau: 200
• Form: powder or crystals
• Farbe: white to light yellow
• Wirkungsspektrum von Antibiotika: Gram-negative bacteria; Gram-positive bacteria
• Wirkungsweise: cell wall synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: [Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C([O-])=O)c3ccsc3)C(=O)N2[C@H]1C([O-])=O
• InChI: 1S/C15H16N2O6S2.2Na/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6;;/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23);;/q;2*+1/p-2/t7-,8-,9+,12-;;/m1../s1
• InChIKey: ZBBCUBMBMZNEME-QBGWIPKPSA-L

Beschreibung

Allgemeine Beschreibung

Chemical structure: ß-lactam

Anwendung

Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination with clavulanate in order to improve it′s efficacy. It is used to study appropriate dosing in pediatric patients who have cystic fibrosis.

Biochem./physiol. Wirkung

Ticarcillin is a β-Lactam antibiotic that prevents bacterial cell wall biosynthesis at the level of peptidogylcan cross-linking by inhibiting peptidoglycan transpeptidases. It is derived from penicillin and is similar to carbenicillin in action. Ticarcillin is susceptible to degradation by ß-lactamases.

Verpackung

1G

Sonstige Hinweise

β-Lactam antibiotic

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

Lagerung und Haltbarkeit

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H319,H334,H335
• P-Sätze: P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves