T1941

Anti-TrkB antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(e): Anti-DEE58, Anti-EIEE58, Anti-GP145-TrkB, Anti-OBHD, Anti-TRKB, Anti-trk-B
• MDL-Nummer: MFCD01092509
• UNSPSC-Code: 51111800
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: goat
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: lyophilized powder
• Speziesreaktivität: human
• Methode(n): flow cytometry: 2.5 μg/mL (per 10⁶ cells); western blot: 0.25-0.5 μg/mL
• UniProt-Hinterlegungsnummer: Q16620
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... NTRK2(4915)

Beschreibung

Allgemeine Beschreibung

The antibody recognizes recombinant human TrkB. It shows no cross-reactivity with TrkC, NT-3, NT-4, BDNF and NGF-β.

Immunogen

recombinant human TrkB extracellular domain expressed in NS0 cells.

Biochem./physiol. Wirkung

The development and maintenance of central and peripheral nervous system is controlled by a family of Trk family of neurotrophin receptors. The Trk family consists of 3 members, TrkA (NTRK1), Trk B (NTRK2) and TrkC (NTRK3). Neurotrophins have an important role in development of the nervous system and mediate the cellular effects by binding to the Trk receptors. Trk receptors reportedly play a major role in the development and behaviour of neuroblastomas and other type of cancers.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline containing 5% trehalose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable