P9178

Prochlorperazin -dimaleat (Salz)

• Empirische Formel (Hill-System): C₂₀H₂₄ClN₃S · 2C₄H₄O₄
• CAS-Nummer: 84-02-6
• Molekulargewicht: 606.09
• EG-Nummer: 201-511-3
• MDL-Nummer: MFCD00069330
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 57654570
• NACRES: NA.77

Eigenschaften

• Form: powder
• Qualitätsniveau: 200
• Löslichkeit: H₂O: slightly soluble 0.3 mg/mL; 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL; methanol: soluble
• Ersteller: GlaxoSmithKline
• SMILES String: OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1
• InChI: 1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
• InChIKey: DSKIOWHQLUWFLG-SPIKMXEPSA-N
• Angaben zum Gen: human ... DRD2(1813)

Beschreibung

Biochem./physiol. Wirkung

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist; antispasmodic

Leistungsmerkmale und Vorteile

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H336,H361d,H362
• P-Sätze: P202 - P260 - P263 - P264 - P301 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves