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Merck

SRP8033

Sigma-Aldrich

IL-1β mouse

recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)

Synonym(e):

Interleukin-1beta, Postn

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.32

Biologische Quelle

mouse

Rekombinant

expressed in E. coli

Konjugat

untagged

Assay

>95% (SDS-PAGE)

Form

lyophilized

Mol-Gew.

~17 kDa by SDS-PAGE

Verpackung

pkg of 10 μg

Lagerbedingungen

avoid repeated freeze/thaw cycles

Methode(n)

immunohistochemistry: suitable

Verunreinigungen

<0.1 EU/μg endotoxin, tested

Farbe

white

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

mouse ... Il1b(16176)

Allgemeine Beschreibung

Interleukin-1β (IL-1β) is produced by activated macrophages. It belongs to the IL-1 family of proteins that are involved in the inflammatory response.

Biochem./physiol. Wirkung

Interleukin-1β (IL-1β) stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1β, in most situations requires the inflammasome complex to be cleaved and secreted. This protein may modulate the effects of eosinophils in the intestine.

Physikalische Form

Lyophilized from PBS.

Rekonstituierung

Reconstitute with 100 μL deionized water.

Sonstige Hinweise

Mouse IL-1beta (aa 118-269) is untagged.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Die Dokumentenbibliothek aufrufen

IL-1? in eosinophil-mediated small intestinal homeostasis and IgA production.
Jung Y
Mucosal Immunology, 8(4), 930-942 (2015)
Understanding the mechanism of IL-1? secretion.
Lopez-Castejon G and Brough D
Cytokine & Growth Factor Reviews, 22(4), 189-195 (2011)
Ruojia Ma et al.
Drug development research, 83(3), 735-744 (2021-12-21)
Type 2 diabetes mellitus (T2DM) is a metabolic risk factor associated with non-alcoholic liver disease (NAFLD). Schisandrin B (Sch B) is a promising agent for NAFLD. However, the actions of Sch B on diabetes-associated NAFLD and the underlying mechanisms are
Anna Motterle et al.
Diabetologia, 58(8), 1827-1835 (2015-06-04)
Exposure of pancreatic beta cells to cytokines released by islet-infiltrating immune cells induces alterations in gene expression, leading to impaired insulin secretion and apoptosis in the initial phases of type 1 diabetes. Long non-coding RNAs (lncRNAs) are a new class
Shaffi Manchanda et al.
Molecular and cellular biochemistry, 449(1-2), 63-72 (2018-03-20)
Chronic sleep loss/fragmentation prevalent in the current 24/7 society is associated with irreversible consequences on health and overall wellbeing. Various studies have well documented the ill effects of acute sleep loss on cognitive functions of individuals; however, the underlying mechanism

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