I4777

Interferon-γ from mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• Synonym(e): IFN-γ
• MDL-Nummer: MFCD00131391
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 200
• Rekombinant: expressed in E. coli
• Assay: ≥98% (SDS-PAGE)
• Form: lyophilized powder
• Mol-Gew.: protein 15.6 kDa
• Verpackung: pkg of 0.1 mg
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: endotoxin, tested
• Farbe: white
• Löslichkeit: water: soluble 1.000 mL, clear, colorless
• UniProt-Hinterlegungsnummer: P01580
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Ifng(15978)

Beschreibung

Anwendung

Interferon-γ from mouse has been used:

• for in vitro stimulation of the BMDC (bone marrow derived dendritic cell), BMM (bone marrow-derived macrophages) and CD11c⁺ (CD11 antigen-like family member C) lung macrophages
• for stimulation of murine macrophages to induce the production of nitrite and nitrate
• to check CCAAT/enhancer binding protein β (C/EBPβ)-mediated changes in the expression of prostaglandin synthesis enzymes in neuroinflammation

Biochem./physiol. Wirkung

Ifng (interferon-γ) plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.

Physikalische Form

Lyophilized from a 0.2 μm filtered buffered solution. Package size based on protein content.

Hinweis zur Analyse

The biological activity of recombinant mouse IFN-γ is measured by its ability to inhibit the proliferation of murine WEHI-279 cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)