SML2980

G6PDi-1

≥98% (HPLC)

• Synonym(e): 4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
• Empirische Formel (Hill-System): C₁₄H₁₂N₄OS
• CAS-Nummer: 2457232-14-1
• Molekulargewicht: 284.34
• MDL-Nummer: MFCD32899271
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1

Beschreibung

Biochem./physiol. Wirkung

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable