SML2533

Jedi1

≥98% (HPLC)

• Synonym(e): 2-Methyl-5-phenyl-3-furancarboxylic acid, 2-Methyl-5-phenyl-3-furoic acid, 2-Methyl-5-phenylfuran-3-carboxylic acid, 5-Phenyl-2-methyl-3-furancarboxylic acid
• Empirische Formel (Hill-System): C₁₂H₁₀O₃
• CAS-Nummer: 108124-17-0
• Molekulargewicht: 202.21
• UNSPSC-Code: 12352302
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14)/p-1
• InChIKey: VLMNACSEESRUAK-UHFFFAOYSA-M

Beschreibung

Biochem./physiol. Wirkung

Jedi1 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable