SML2532

Jedi2

≥98% (HPLC)

• Synonym(e): 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
• Empirische Formel (Hill-System): C₁₀H₈O₃S
• CAS-Nummer: 651005-90-2
• Molekulargewicht: 208.23
• MDL-Nummer: MFCD01569561
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
• InChIKey: YXDCRSXNEOKXDE-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Jedi2 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H317,H319
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable