SML2114

ZD7155 hydrochloride

≥97% (HPLC)

• Synonym(e): 5,7-Diethyl-3,4-dihydro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one hydrochloride, ZD 7155
• Empirische Formel (Hill-System): C₂₆H₂₆N₆O · HCl
• CAS-Nummer: 146709-78-6
• Molekulargewicht: 474.99
• MDL-Nummer: MFCD00921888
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥97% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 2 mg/mL, clear (warmed)
• Lagertemp.: 2-8°C
• SMILES String: CCC1=C(C2=CC(CC)=N1)CCC(N2CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5)=O.Cl
• InChI: 1S/C26H26N6O.ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H
• InChIKey: NAGGAAHTUXEGFG-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ZD7155 is a potent selective Angiotensin II AT1 antagonist. In one study ZD 7155 was found to be longer-acting and approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3