SML0956

Dexmedetomidin -hydrochlorid

≥98% (HPLC)

• Synonym(e): (+)-Medetomidin -hydrochlorid, (S)-Medetomidin -hydrochlorid, 4-[(S)-α,2,3-Trimethylbenzyl-]imidazol -monohydrochlorid, 5-[(1S)-1-(2,3-Dimethylphenyl)-ethyl]-1H-imidazol -hydrochlorid
• Empirische Formel (Hill-System): C₁₃H₁₆N₂ · HCl
• CAS-Nummer: 145108-58-3
• Molekulargewicht: 236.74
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +48 to +58°, c = 1 in H₂O
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
• InChIKey: VPNGEIHDPSLNMU-MERQFXBCSA-N

Beschreibung

Anwendung

Dexmedetomidine hydrochloride has been used to study its effects on primary neonatal rat cardiomyocytes under hypoxic/reoxygenation conditions. It has also been used to study the effects of dexmedetomidine pretreatment on lipopolysaccharide-induced acute lung injury in mice.

Biochem./physiol. Wirkung

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.

Leistungsmerkmale und Vorteile

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Sonstige Hinweise

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Sicherheitshinweise

• Piktogramme: GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H336,H411
• P-Sätze: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable