SML0733

Cilomilast

≥95% (HPLC)

• Synonym(e): SB 207499, SB-207499, cis-4-Cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid
• Empirische Formel (Hill-System): C₂₀H₂₅NO₄
• CAS-Nummer: 153259-65-5
• Molekulargewicht: 343.42
• UNSPSC-Code: 41106305
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 15 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: N#CC3(CCC(CC3)C(=O)O)c1cc(c(cc1)OC)OC2CCCC2
• InChI: 1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)
• InChIKey: CFBUZOUXXHZCFB-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Cilomilast (SB-207499) is a potent, selective and orally available PDE4 inhibitor that exhibits anti-inflamatory and anti-asthmatic activity.

Cilomilast (SB-207499) is a potent, selective and orally available PDE4 inhibitor.

Leistungsmerkmale und Vorteile

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable