SML0397

DR2313

≥98% (HPLC)

• Synonym(e): 3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
• Empirische Formel (Hill-System): C₈H₁₀N₂OS
• CAS-Nummer: 284028-90-6
• Molekulargewicht: 182.24
• MDL-Nummer: MFCD08703132
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825393
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: H₂O: >2 mg/mL (warmed)
• Lagertemp.: 2-8°C
• SMILES String: CC1=NC(=O)C2=C(CCSC2)N1
• InChI: 1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
• InChIKey: HRYKZAKEAVZGJD-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.

Leistungsmerkmale und Vorteile

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable