SML0295

Dihydromyricetin

≥98% (HPLC)

• Synonym(e): (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-on, 3,3′,4′,5,5′,7-Hexahydroxyflavanon, Ampelopsin, Ampeloptin, DHM
• Empirische Formel (Hill-System): C₁₅H₁₂O₈
• CAS-Nummer: 27200-12-0
• Molekulargewicht: 320.25
• MDL-Nummer: MFCD00189451
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825302
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: protect from light
• Farbe: white to beige
• Löslichkeit: DMSO: ≥5 mg/mL (warmed)
• Lagertemp.: −20°C
• SMILES String: O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(C(O)=C3)O)[C@H]1O
• InChI: 1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
• InChIKey: KJXSIXMJHKAJOD-LSDHHAIUSA-N

Beschreibung

Allgemeine Beschreibung

Dihydromyricetin is a major flavonoid present in A. grossedentata.

Anwendung

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

Biochem./physiol. Wirkung

Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity, found to have anti-alcohol intoxication effects. Its anti-alcohol effects appear to be by its actions as a positive modulator of GABA-A receptors at the benzodiazepine site.

Dihydromyricetin possesses anti-inflammatory action.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable