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Supelco

Lupeol

analytical standard

Synonym(e):

β-Viscol, 20(29)-Lupen-3β-ol, 3β-Hydroxy-20(29)-lupen, Clerodol, Fagarasterol, Lupenol, Monogynol B

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About This Item

Empirische Formel (Hill-System):
C30H50O
CAS-Nummer:
545-47-1
Molekulargewicht:
426.72
EG-Nummer:
208-889-9
MDL-Nummer:
MFCD00017351
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329751732
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Assay

≥90.0% (GC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

2-8°C

SMILES String

[H]C12CCC3C4(C)CCC(O)C(C)(C)[C@]4([H])CCC3(C)[C@]1(C)CCC5(C)CC[C@H](C(C)=C)[C@]25[H]

InChI

1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3/t20-,21+,22-,23+,24-,25+,27+,28-,29+,30+/m0/s1

InChIKey

MQYXUWHLBZFQQO-QGTGJCAVSA-N

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Allgemeine Beschreibung

Lupeol is a novel anti-cancer and anti-inflammatory dietary triterpene. They help in stabilizing phospholipid bilayers in plant cell membranes. In general, this group contains 28-29 carbons along with carbon-carbon double bonds, usually one in the sterol nucleus and at times a second in the alkyl side chain.

Anwendung

It was used as reference standard in method development and validation of lupeol from Vernonia Cinerea using HPLC method.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

This compound is commonly found in plants of the genus: glycyrrhiza sambucus

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCF8940
BCCC6897
BCBZ6801
BCBW5994
BCBT4459

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Sigma-Aldrich

855022

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Sigma-Aldrich

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Sigma-Aldrich

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Betulinsäure

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Sigma-Aldrich

855057

Betulinsäure

Oleanolsäure analytical standard

Supelco

42515

Oleanolsäure

Archana Kumari et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1781-1789 (2012-03-13)
Drug induced hepatotoxicity is a major problem where phytochemicals hold promise for its abrogation. This study was carried out to explore cytoprotective potential of lupeol, a triterpene, against acetaminophen (AAP)-induced toxicity in rat hepatocytes. AAP exposure significantly (p<0.05) reduced cell
Mohammad Saleem
Cancer letters, 285(2), 109-115 (2009-05-26)
In the Western world, an average of 250 mg per day of triterpenes (member of phytosterol family), largely derived from vegetable oils, cereals, fruits and vegetables is consumed by humans. During the last decade, there has been an unprecedented escalation
Edwin Ogechukwu Omeje et al.
Natural product research, 26(19), 1775-1781 (2011-10-20)
Column fractionation and purification of an n-hexane fraction led to the isolation of three lupeol-based triterpenoid esters from the leaves of the Eastern Nigeria mistletoe, Loranthus micranthus Linn parasitic on a local kola nut tree, Kola acuminata. These three compounds
Pranav K Chaturvedi et al.
Cancer letters, 263(1), 1-13 (2008-03-25)
The perception of chemoprevention lies still in its infancy. Intervention, to slow down, arrest or reverse the process of carcinogenesis, by the use of either natural or synthetic substances individually or in combination therapy has emerged as a promising and
Archana Kumari et al.
Life sciences, 90(15-16), 561-570 (2012-02-14)
Lupeol, a triterpene, possesses numerous pharmacological activities, including anti-malarial, anti-arthritic and anti-carcinogenic properties. The present study was conducted to explore the hepatoprotective potential of lupeol against acetaminophen (AAP)-induced hepatotoxicity in Wistar rats. Rats were given a prophylactic treatment of lupeol
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