SAB5701767

Anti-Phospho-α-Synuclein-S129 antibody produced in rabbit

• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: liquid
• Speziesreaktivität: human
• Konzentration: 1.35 mg/mL
• Methode(n): western blot: 1:500-1:1000
• UniProt-Hinterlegungsnummer: P37840
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer129 )
• Angaben zum Gen: human ... SNCA(6622)

Beschreibung

Allgemeine Beschreibung

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer′s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S129 of human alpha-Synuclein

Physikalische Form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable