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Key Documents

SAB5201104

Sigma-Aldrich

Monoclonal Anti-Gfap antibody produced in mouse

clone S206A-8, purified immunoglobulin

Synonym(e):

Anti-Astrocyte, Anti-Glial fibrillary acidic protein, Anti-MGC139638

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

S206A-8, monoclonal

Form

buffered aqueous solution

Mol-Gew.

antigen predicted mol wt 50 kDa

Speziesreaktivität

rat, mouse, human

Konzentration

1 mg/mL

Methode(n)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NP_001124491.1

UniProt-Hinterlegungsnummer

P14136

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... GFAP(2670)

Immunogen

Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP; 100% identical in rat and mouse

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

PBS pH 7.4, 50% glycerol, 0.1% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Benoit Michot et al.
Neuroscience letters, 653, 113-119 (2017-05-24)
The differential pharmacological responsiveness of cephalic and extra-cephalic neuropathic pain has been proposed to relate to distinct mechanisms that may involve neuroinflammatory reactions mediated by glial cells. Astrocytes are particularly important for neuronal sensitization in neuropathic pain, in part through
Razvan Vlad Opris et al.
Nanomaterials (Basel, Switzerland), 12(1) (2022-01-12)
(1) Background: The study aimed to assess neurobehavioral, ultrastructural, and biochemical changes induced by silver nanoparticles synthesized with Cornus mas L. extract (AgNPs-CM) in rat brains. (2) Methods: The study included 36 male adult rats divided into three groups. Over
Hui Li et al.
Journal of inflammation research, 16, 95-107 (2023-01-17)
The spinal cord expresses brain-derived neurotrophic factor precursor (proBDNF) and its receptor pan neurotrophin receptor 75 (p75NTR). However, the role of spinal proBDNF signaling in the pathogenesis of inflammatory pain remains unknown. Rats were locally injected with complete Freund's adjuvant
Jordon Dunham et al.
PloS one, 12(11), e0188013-e0188013 (2017-11-15)
Oxidative stress is increasingly implicated as a co-factor of tissue injury in inflammatory/demyelinating disorders of the central nervous system (CNS), such as multiple sclerosis (MS). While rodent experimental autoimmune encephalomyelitis (EAE) models diverge from human demyelinating disorders with respect to
Jian Wang et al.
Molecular medicine reports, 24(6) (2021-10-06)
Angina pectoris is cardiac pain that is a common clinical symptom often resulting from myocardial ischemia. Spinal cord stimulation (SCS) is effective in treating refractory angina pectoris, but its underlying mechanisms have not been fully elucidated. The spinal dorsal horn
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