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Merck

SAB5200073

Sigma-Aldrich

Monoclonal Anti-KCNIP3 antibody produced in mouse

clone S66-38, 1 mg/mL, purified immunoglobulin

Synonym(e):

Anti-Csen, Anti-Dream, Anti-KChlP3 K+ channel, S66-38, Anti-Kcnip3, Anti-rKChIP3

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

S66-38, monoclonal

Form

buffered aqueous glycerol solution

Mol-Gew.

antigen predicted mol wt 34 kDa

Speziesreaktivität

mouse, human, rat

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG2a

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Allgemeine Beschreibung

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is part of the neuronal calcium sensor protein family. The gene ID of the protein is 65199.

Spezifität

Detects ~34 kDa. No cross reactivity against KCIPs 1,2 or 4

Immunogen

Fusion protein amino acids 1-256 (Full lenght) of rat Calsenillin/DREAM/KChIP3

Biochem./physiol. Wirkung

Potassium voltage-gated channel interacting protein 3 (KCNIP3) is involved in the downregulation of other genes. It has been shown that the protein is upregulated when there is a high concentration of glucose in vitro.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Rosfaiizah Siran et al.
Journal of physiology and biochemistry, 70(4), 877-889 (2014-09-15)
REM sleep is a crucial component of sleep. Animal studies indicate that rapid eye movement (REM) sleep deprivation elicits changes in gene expression. Down regulatory antagonist modulator (DREAM) is a protein which downregulates other gene transcriptions by binding to the
Erika Chavira-Suárez et al.
Biochemical and biophysical research communications, 418(2), 420-425 (2012-01-27)
Hyperglycemia alters the tight control of intracellular calcium dynamics in retinal cells and may lead to the development of diabetic retinopathy. The potassium channel interacting protein 3 (KChIP3) also known as DREAM (Downstream Regulatory Element Antagonist Modulator) or calsenilin (KChIP3/DREAM/calsenilin)

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