SAB4500379

Anti-TSH2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): OVC10-2, Ovarian cancer-related protein 10-2, Zinc finger protein 218
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 115 kDa
• Speziesreaktivität: human, mouse
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• NCBI-Hinterlegungsnummer: Q9NRE2
• UniProt-Hinterlegungsnummer: Q9NRE2
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TSHZ2(128553)

Beschreibung

Allgemeine Beschreibung

Anti-TSH2 Antibody detects endogenous levels of total TSH2 protein.

TSH2/TSHZ2 (teashirt zinc finger homeobox 2) is a nuclear protein. It has four zinc-finger (ZF) domains, a homeobox domain and a coiled-coil domain. It is located on human chromosome 20q13.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human TSH2.

Immunogen Range: 811-860

Biochem./physiol. Wirkung

TSH2/TSHZ2 (teashirt zinc finger homeobox 2) acts as a C-terminal binding protein (CtBP)-dependent transcriptional repressor. At the time of mammary tumorigenesis, low level expression of TSH2 liberates GLI1 (glioma-associated oncogene homolog 1) from the nuclear repressor complex to update its transcriptional activity.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable