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SAB4300614

Sigma-Aldrich

Anti-ARNTL antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-BMAL1 antibody produced in rabbit, Anti-BMAL1c antibody produced in rabbit, Anti-JAP3 antibody produced in rabbit, Anti-MGC47515 antibody produced in rabbit, Anti-aryl hydrocarbon receptor nuclear translocator-like antibody produced in rabbit

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About This Item

MDL-Nummer:
MFCD02262590
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~69 kDa

Speziesreaktivität

rat, mouse, human

Konzentration

1 mg/mL

Methode(n)

western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(S-S-S-I-L)

NCBI-Hinterlegungsnummer

NP_001025443.1

UniProt-Hinterlegungsnummer

O00327

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ARNTL(406)

Immunogen

Peptide sequence around aa. 569-573 (S-S-S-I-L), according to the protein ARNTL.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Brian A Hodge et al.
Skeletal muscle, 5, 17-17 (2015-05-23)
Skeletal muscle is a major contributor to whole-body metabolism as it serves as a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within skeletal muscle exists an intrinsic molecular clock mechanism that regulates the
Brian A Hodge et al.
eLife, 8 (2019-02-23)
In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1
Michael L Rossetti et al.
American journal of physiology. Endocrinology and metabolism, 317(4), E631-E645 (2019-07-31)
Androgen depletion in humans leads to significant atrophy of the limb muscles. However, the pathways by which androgens regulate limb muscle mass are unclear. Our laboratory previously showed that mitochondrial degradation was related to the induction of autophagy and the

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