SAB4300167

Anti-phospho-CDKN1B (pThr¹⁸⁷) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-CDKN4 antibody produced in rabbit, Anti-KIP1 antibody produced in rabbit, Anti-MEN1B antibody produced in rabbit, Anti-MEN4 antibody produced in rabbit, Anti-cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody produced in rabbit
• MDL-Nummer: MFCD00284080
• UNSPSC-Code: 12352203
• NACRES: NA.43

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~27 kDa
• Speziesreaktivität: human
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (E-Q-TP-P-K)
• NCBI-Hinterlegungsnummer: NP_004055.1
• UniProt-Hinterlegungsnummer: P46527
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pThr187)
• Angaben zum Gen: human ... CDKN1B(1027)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of threonine 187 (E-Q-T(p)-P-K), according to the protein CDKN1B.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable