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Merck

SAB3500380

Sigma-Aldrich

Anti-LXR-B antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-LXRB, Anti-Liver X receptor B, Anti-NR1H2, Anti-Nuclear receptor subfamily 1 group H member 2

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, human, rat

Methode(n)

indirect ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NR1H2(7376)

Allgemeine Beschreibung

Liver X receptor β (LXRβ ) is a member of LXRs that belong to the nuclear receptor superfamily. It possesses a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The protein is expressed in many tissues and the LXRβ gene is localized on human chromosome 19q13.3.

Immunogen

LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.

Biochem./physiol. Wirkung

Liver X receptor β (LXRβ) has a role in cell death and cholesterol metabolism. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3500380.

Physikalische Form

Supplied in PBS with 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.
Mouzat K
BMC Medical Genetics (2011)
Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells.
Derangere V
Cell Death and Differentiation (2014)
Liver x receptors in atherosclerosis and inflammation.
Im SS and Osborne TF
Circulation Research (2011)

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