S7796

Sisomicin -sulfat (Salz)

≥580 μg/mg (USP)

• Synonym(e): O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1->6))-2-deoxy-L-streptamine sulfate (2:5) (salt)
• Empirische Formel (Hill-System): C₁₉H₃₇N₅O₇ · 2.5H₂O₄S
• CAS-Nummer: 53179-09-2
• Molekulargewicht: 692.72
• EG-Nummer: 258-414-4
• UNSPSC-Code: 51281665
• PubChem Substanz-ID: 329824589
• NACRES: NA.85

Eigenschaften

• Form: powder
• Konzentration: ≥580 μg/mg (USP)
• Farbe: white to off-white
• Wirkungsspektrum von Antibiotika: Gram-negative bacteria
• Wirkungsweise: protein synthesis | interferes
• Lagertemp.: −20°C
• SMILES String: OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3OC(CN)=CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6OC(CN)=CC[C@H]6N)[C@@H]5O
• InChI: 1S/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+;;;;;/m11...../s1
• InChIKey: CIKNYWFPGZCHDL-ZHFUJENKSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: aminoglycoside

Anwendung

Sisomicin is an aminoglycoside antibiotic isolated from Micromonopora inyoensis. It is effective against most strains of Klebsiellk spp., Escherichia coli, P. aeruginosa, Enterobacter and Proteus spp.. It is a potential treatment for conjunctiva . It is used in disk and tube dilution sensitivity test.

Biochem./physiol. Wirkung

Sisomicin interferes with protein synthesis at the level of functional ribosome assembly. The mechanism is similar to that of gentamycin. Sisomicin closely resembles gentamicin but is more effective against Pseudomonas aeruginosa and indole-positive Proteus.

Verpackung

250MG,1G,5G

Lagerung und Haltbarkeit

Keep container tightly closed in a dry and well-ventilated place.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H312 + H332,H360
• P-Sätze: P202 - P261 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges