S1198

Sumatriptan-Succinat

≥98% (HPLC), solid, 5-HT₁ receptor agonist

• Synonym(e): 3-[2-(Dimethylamino)-ethyl]-N-methyl-1H-indol-5-methansulfonamid-succinat, GR-43175
• Empirische Formel (Hill-System): C₁₄H₂₁N₃O₂S · C₄H₆O₄
• CAS-Nummer: 103628-48-4
• Molekulargewicht: 413.49
• MDL-Nummer: MFCD00902856
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329824466
• NACRES: NA.77

Eigenschaften

• product name: Sumatriptan-Succinat, ≥98% (HPLC), solid
• Assay: ≥98% (HPLC)
• Form: solid
• Farbe: white to beige
• Löslichkeit: H₂O: >20 mg/mL
• Ersteller: GlaxoSmithKline
• SMILES String: OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1
• InChI: 1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
• InChIKey: PORMUFZNYQJOEI-UHFFFAOYSA-N
• Angaben zum Gen: human ... HTR1B(3351) , HTR1D(3352)

Beschreibung

Biochem./physiol. Wirkung

Sumatriptan succinate has the ability to constrict human cranial arteries. This 5-HT₁ receptor agonist can be used to treat migraine.

Sumatriptan-succinat ist ein Serotonin 5-HT1-Rezeptor-Agonist.

Leistungsmerkmale und Vorteile

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• H-Sätze: H361d,H412
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Aquatic Chronic 3 - Repr. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves