P7556

Progesteron-Wasser, löslich

powder, BioReagent, suitable for cell culture

• Synonym(e): Progesteron: 2-hydroxypropyl-β-cyclodextrin-Komplex, Progesteron: HBC-Komplex
• MDL-Nummer: MFCD00003658
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 57654558
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Produktlinie: BioReagent
• Form: powder
• Konzentration: ≥65% (HPLC)
• Methode(n): cell culture | mammalian: suitable
• Löslichkeit: H₂O: 25 mg/mL, clear to slightly hazy
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• InChIKey: RJKFOVLPORLFTN-LEKSSAKUSA-N
• Angaben zum Gen: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

Beschreibung

Allgemeine Beschreibung

Progesterone is a steroid hormone secreted by the ovaries.

Anwendung

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

Biochem./physiol. Wirkung

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

Verpackung

Package size based on progesterone content

Sonstige Hinweise

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H351,H360FD,H362
• P-Sätze: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Gefahreneinstufungen: Carc. 2 - Lact. - Repr. 1A
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable