N4256

Nicotinic acid adenine dinucleotide sodium salt

≥98%

• Synonym(e): Deamido NAD, Deamido NAD Sodium Salt, NAAD, NAAD Sodium Salt, Nicotinic Acid Adenine Dinucleotide Sodium Salt, Nicotinic Acid NAD Sodium Salt, Nicotinic acid NAD
• Empirische Formel (Hill-System): C₂₁H₂₅N₆O₁₅P₂Na
• CAS-Nummer: 104809-30-5
• Molekulargewicht: 686.39
• MDL-Nummer: MFCD00082430
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24897698
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (inorganic)
• Qualitätsniveau: 200
• Assay: ≥98%
• Form: powder
• Löslichkeit: H₂O: soluble-50 mg/mL, clear, colorless
• Lagertemp.: −20°C
• SMILES String: [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OCC4OC(C(O)C4O)[N]5=CC(=CC=C5)C(O)=O)C(O)C3O
• InChI: 1S/C21H27N6O15P2.Na.H/c22-17-12-18(24-7-23-17)27(8-25-12)20-16(31)14(29)11(41-20)6-39-44(36,37)42-43(34,35)38-5-10-13(28)15(30)19(40-10)26-3-1-2-9(4-26)21(32)33;;/h1-4,7-8,10-11,13-16,19-20,28-31H,5-6H2,(H,32,33)(H,34,35)(H,36,37)(H2,22,23,24);;
• InChIKey: JSOFOHZYBCRUNK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Nicotinic acid adenine dinucleotide (deamido-NAD, NAAD) is a closely related analog of NAD⁺. It is used to study the structure of nicotinate mononucleotide adenylyltransferase(s) (NMN/NaMN). NAAD is used as a substrate to study the specificity and kinetics of nicotinamide adenine dinucleotide synthetase(s) (NADS). In addition, it is also used as a co-substrate to study mechanisms of members of the Sir2 class of NAD⁺-dependent deacetylase.

Anwendung

Nicotinic acid adenine dinucleotide sodium salt has been used as an internal standard during high performance liquid chromatography (HPLC) metabolite measurement. It has also been used as a substrate in nicotinamide adenine dinucleotide (NAD) biosynthesis.

Sonstige Hinweise

Analog of β-NAD

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves