M9191

Microsomes from Liver, Pooled

from rat(Sprague-Dawley), female

• Synonym(e): lab equipment accessory
• UNSPSC-Code: 12161501
• NACRES: NA.47

Eigenschaften

• Biologische Quelle: rat (Sprague-Dawley)
• Qualitätsniveau: 200
• Form: liquid
• Spezifische Aktivität: ≥20 units/mg protein, pH 7.4, 37 °C
• Verpackung: vial of ~10 mg
• Versandbedingung: dry ice
• Lagertemp.: −70°C

Beschreibung

Biochem./physiol. Wirkung

Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions.

Einheitendefinition

One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C.
7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable