M3895

Mucin aus Rinderunterkieferdrüse

Type I-S

• Synonym(e): MUC
• CAS-Nummer: 84195-52-8
• EG-Nummer: 282-357-4
• MDL-Nummer: MFCD00131629
• UNSPSC-Code: 12352202
• NACRES: NA.61

Eigenschaften

• Biologische Quelle: bovine submaxillary glands
• Typ: Type I-S
• Form: powder
• Zusammensetzung: Bound sialic acids, 9-24%
• Methode(n): electrophoresis: suitable
• UniProt-Hinterlegungsnummer: P98091
• Lagertemp.: −20°C
• Angaben zum Gen: cow ... BSM(286841)

Beschreibung

Allgemeine Beschreibung

Mucin from bovine submaxillary glands is encoded by two bovine submaxillary BSM genes. It is present in the saliva and interacts with air and food. Mucin comprises three major domains namely N- and C terminal and the glycosylated proline, threonine and serine (PTS domain) central domain. The sialic acid contributes to 30% of the molecular weight of mucin. The central domain has many tandem repeats.

Anwendung

Mucin from bovine submaxillary glands has been used:

• in the quantification of mucin
• as a component of artificial tear solution
• as a substrate for recombinant sialidase Gardnerella vaginalis
• to investigate a galactose-specific lectin from the red marine alga Ptilota filicina
• to study the characterization of a unique mucin-like glycoprotein secreted by a human endometrial adenocarcinoma cell line (Ishikawa)

Biochem./physiol. Wirkung

Bovine submaxillary mucin (BSM) is thermally stable up to 85°C. The terminal domain regions are key for the adsorption functionality of mucin.

Albuminoid substance in mucus which gives it its ropy consistency

Verlinkung

Similar to M 4503, but produced by Sigma.

Substrate

Neuraminidase substrate.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)