M3781

6α-Methylprednisolon 21-Hemisuccinat Natriumsalz

lyophilized powder

• Synonym(e): 6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate
• Lineare Formel: C₂₆H₃₃O₈Na
• CAS-Nummer: 2375-03-3
• Molekulargewicht: 496.53
• EG-Nummer: 219-156-8
• MDL-Nummer: MFCD00152612
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24896873
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 100
• Sterilität: non-sterile
• Assay: ≥98.00% (TLC)
• Form: lyophilized powder
• Methode(n): toxicology assay: suitable
• Löslichkeit: water: 50 mg/mL, clear, colorless to faintly yellow
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: [Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14
• InChI: 1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
• InChIKey: FQISKWAFAHGMGT-SGJOWKDISA-M
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Anwendung

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.

Biochem./physiol. Wirkung

Glucocorticoid with slightly longer half-life than that of prednisolone.

Physikalische Form

Lyophilized containing ~5% phosphate buffer salts.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H351,H360
• P-Sätze: P201 - P308 + P313
• Gefahreneinstufungen: Carc. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges