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Merck

L3750

Sigma-Aldrich

β-Laktose

≤30% α-anomer basis, ≥99% total lactose basis

Synonym(e):

β-D-Gal-(1→4)-β-D-Glc

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About This Item

Empirische Formel (Hill-System):
C12H22O11
CAS-Nummer:
Molekulargewicht:
342.30
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.25

Biologische Quelle

bovine milk

Assay

≥99% total lactose basis

Form

powder

Konzentration

≥30% (α-anomer)

Farbe

white to off-white

Löslichkeit

water: 50 mg/mL, clear, colorless

Lagertemp.

room temp

SMILES String

OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1

InChIKey

GUBGYTABKSRVRQ-DCSYEGIMSA-N

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Allgemeine Beschreibung

Lactose is an important disaccharide in human nutrition, culinary goods, and pharmaceuticals. β-lactose is an isomeric form that is rarely found in nature.

Anwendung

β-Lactose has been used:
  • to treat HL-1 cells followed by phorbol dibutyrate (PDB) treatment to study if protein kinase C (PKC) -stimulated accumulation is mediated through galectin-3
  • as a component of a media to analyze the extracellular production of protein
  • along with recombinant galectin-3 to treat cells for the detection of galectin-3 cell surface binding
  • along with recombinant galectin-3 or a control protein to stimulate T cells for apoptosis assay

Biochem./physiol. Wirkung

Beta-Lactose is the beta-pyranose form of the compound lactose.
Lactose, an excipient in a various medication, is used as an additive in a variety of foods. It is utilized as a commercial additive in the food industry due to its texture, flavor, and adhesive characteristics.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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Phytopathology, 85(11), 1428-1435 (1995)
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The SARS-CoV-2 pandemic has created an unprecedented need for rapid diagnostic testing to enable the efficient treatment and mitigation of COVID-19. The primary diagnostic tool currently employed is reverse transcription polymerase chain reaction (RT-PCR), which can have good sensitivity and
Logan K Smith et al.
eLife, 10 (2021-08-10)
Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that restrain B cell responses to low-affinity endogenous antigens are not
Benjamin D Grant et al.
PloS one, 16(11), e0258819-e0258819 (2021-11-11)
Inexpensive, simple, rapid diagnostics are necessary for efficient detection, treatment, and mitigation of COVID-19. Assays for SARS-CoV2 using reverse transcription polymerase chain reaction (RT-PCR) offer good sensitivity and excellent specificity, but are expensive, slowed by transport to centralized testing laboratories

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