I1521

DES (1-6) IGF II

lyophilized powder, recombinant, expressed in E. coli, suitable for cell culture

• CAS-Nummer: 141909-47-9
• MDL-Nummer: MFCD00285687
• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥95% (HPLC)
• Form: lyophilized powder
• Wirksamkeit: ≤100 ng/mL ED₅₀
• Mol-Gew.: 6,765 Da
• Verpackung: pkg of 20 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: endotoxin, tested
• Farbe: white
• UniProt-Hinterlegungsnummer: P01344
• Lagertemp.: 2-8°C
• Angaben zum Gen: human ... IGF2(3481)

Beschreibung

Allgemeine Beschreibung

DES (1-6) IGF-II is a 61 amino acid analog of human insulin-like growth factor II, lacking the first six N-terminal amimo acids. DES (1-6) IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which are known to inhibit the actions of IGF′s.

Anwendung

Used for studies of IGF-II function in cell culture applications. Use in combination with IGF-I, insulin and other forms of IGF-II to study receptor functions and cell signaling.

Sonstige Hinweise

Recombinant analog of insulin-like growth factor II.

Angaben zur Herstellung

Prepared from 0.1 M acetic acid.

Synthesized recombinantly in E. coli using a patented fusion protein expression system, DES (1-6) IGF-II is then purified by liquid chromatography. DES (1-6) IGF-II has been developed as an inexpensive, high quality potent analog of IGF-II for use as a growth factor supplement in cell culture. DES (1-6) IGF-II is supplied as a powder, lyophilized from 0.1 M acetic acid. Molecular weight is 6,765 daltons.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)