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Merck

H8636

Sigma-Aldrich

Anti-Haptoglobin antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Synonym(e):

Anti-BP, Anti-HP2ALPHA2, Anti-HPA1S

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

IgG fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

human

Verpackung

vial of 2 mL lyophilized antiserum

Methode(n)

indirect ELISA: 1:30,000

UniProt-Hinterlegungsnummer

Anwendung(en)

research pathology

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... HP(3240)

Allgemeine Beschreibung

Haptoglobin (HP) is encoded by the gene mapped to human chromosome 16q22.2. There are two splice variants of the gene namely, HP1 and HP2.

Immunogen

Human haptoglobin

Anwendung

Anti-Haptoglobin antibody is suitable for use in Ouchterlony double diffusion (1:16) and immunoelectrophoresis.
Anti-Haptoglobin antibody produced in rabbit has been used in immunohistochemistry and western blotting.

Biochem./physiol. Wirkung

Haptoglobin is an antioxidant protein that binds with hemoglobin. Haptoglobin primarily functions to inhibit oxidative damage induced by hemoglobin. Alterations in haptoglobin have been associated with the risk of diabetic vascular disorders such as retinopathy, nephropathy and cardiovascular diseases . Anti-Haptoglobin antibody is specific for haptoglobin in humans.

Physikalische Form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Rekonstituierung

Reconstitute with 2 ml deionized water.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

E Yee et al.
Journal of immunological methods, 225(1-2), 125-130 (1999-06-12)
Three ELISA methods for the quantitation of haptoglobin (Hp) in plasma and albumin are described: a polystyrene direct adsorption method and capture methods with antibody and hemoglobin. Hp aggregates generated by 60 degrees C heating showed as much as a
Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth
McCarthy M, et al.
Placenta, 62(2), 50-57 (2018)
Vivekananda Shetty et al.
Clinical proteomics, 9(1), 10-10 (2012-08-04)
In approximately 80% of patients, ovarian cancer is diagnosed when the patient is already in the advanced stages of the disease. CA125 is currently used as the marker for ovarian cancer; however, it lacks specificity and sensitivity for detecting early
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
Ijas P, et al.
Atherosclerosis, 230(2), 228-234 (2013)
Diminished acute phase response and increased hepatic inflammation of aged rats in response to intraperitoneal injection of lipopolysaccharide
Gomez C, et al.
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 63(12), 1299-1306 (2008)

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