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GW22597F

Sigma-Aldrich

Anti-S100A6 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL-Nummer:
MFCD00677384
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, rat, human

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

NP_055439.1

UniProt-Hinterlegungsnummer

P06703

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... S100A6(6277)

Allgemeine Beschreibung

Protein S100-A6 is a homodimeric protein encoded by the S100A6 gene in humans. It is a member of S100 protein family. It is involved in several biological functions such as cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis.

Immunogen

Immunogen Sequence: GI # 7657532, sequence 1-90
Recombinant S100 calcium-binding protein A6

Anwendung

Anti-S100A6 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Protein S100-A6 is a homodimeric protein encoded by the S100A6 gene in humans and is a member of S100 protein family. It has biological functions in cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis. S100A6 plays an important role in regulating endothelial commitment to, and progression through, the cell cycle. It is involved in several vital biological functions, such as calcium sensing and cell proliferation. S100A6 helps in promoting proliferation and migration of human hepatoma cells. Overexpression results in alteration of E-cadherin and β-catenin and is over expressed in human hepatocellular carcinoma.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Ziqiang Li et al.
Journal of molecular medicine (Berlin, Germany), 92(3), 291-303 (2013-11-28)
High levels of S100A6 have been associated with poor outcome in some types of human cancers, but the role of S100A6 in the molecular pathogenesis of these cancers is largely unknown. This study was performed to explore the expression and
Leyuan Bao et al.
The FEBS journal, 279(24), 4576-4588 (2012-10-26)
Endothelial cells regulate many aspects of vascular physiology, including vasculogenesis and angiogenesis. The S100 family of calcium-binding proteins regulates many aspects of cell function but their roles in vascular physiology are less well understood. Herein, we investigated the expression and
Sepuru K Mohan et al.
Biochemical and biophysical research communications, 434(2), 328-333 (2013-03-30)
S100A6 is involved in several vital biological functions, such as calcium sensing and cell proliferation. It is a homodimeric protein that belongs to the S100 protein family. The receptor for advanced glycation end products (RAGE) has been shown to play
Honglin He et al.
Protein expression and purification, 83(1), 98-103 (2012-03-28)
S100A6, as a member of S100 protein family, have biological functions in cell proliferation, differentiation, morphology, cytoskeletal organization and apoptosis. In the last three decades, S100A6 has been caught more and more attention. Here, we introduced a simple and efficient

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