GW20083F

Anti-Human IgG (Fc specific) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-Immunoglobulin G Fc
• MDL-Nummer: MFCD00162436
• UNSPSC-Code: 12352203
• NACRES: NA.46

Eigenschaften

• Biologische Quelle: chicken
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: rat, human, mouse
• Hersteller/Markenname: Genway 15-288-20083F
• Methode(n): western blot: suitable
• UniProt-Hinterlegungsnummer: P01857
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... IGHG1(3500)

Beschreibung

Immunogen

IgG Fc human native protein.

Anwendung

Anti-Human IgG (Fc specific) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Ig γ-1 chain C region is a protein encoded by the IGHG1 gene in humans. Igγ-1 chain C region is present in human pancreatic cancer tissues and its expression is very low in adjacent noncancerous tissues. IGHG1 blockage leads to retarded tumor growth and improved survival. Its presence in pancreatic cancer cells might constitute an important element that is responsible for tumor cell proliferation and immune evasion mechanisms. IGHG1 is associated with prostate cancer and can inhibit cell viability leading to apoptosis. It may act as a potential target in prostate cancer gene therapy.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)