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G8790

Sigma-Aldrich

Glycin

≥98.5%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Synonym(e):

Aminoessigsäure, Aminoethansäure, Glycokoll

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About This Item

Lineare Formel:
NH2CH2COOH
CAS-Nummer:
56-40-6
Molekulargewicht:
75.07
Beilstein:
635782
EG-Nummer:
200-272-2
MDL-Nummer:
MFCD00008131
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
24895353
NACRES:
NA.26

product name

Glycin, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%

Biologische Quelle

non-animal source

Qualitätsniveau

300

Agentur

meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Assay

≥98.5%

Form

powder

Qualität

meets EP, JP, USP testing specifications

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

endotoxin, tested

Farbe

white

pH-Wert

5.9-6.4

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp (Schmelzpunkt)

240 °C (dec.) (lit.)

Löslichkeit

H2O: 100 mg/mL

SMILES String

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Angaben zum Gen

rat ... Grin2a(24409)

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Anwendung

Amino acid for use in cell culture media development applications and existing media formulations.

Biochem./physiol. Wirkung

Hemmender Neurotransmitter im Rückenmark; allosterischer Regulator von NMDA-Rezeptoren.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Glycin United States Pharmacopeia (USP) Reference Standard

USP

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Glycin European Pharmacopoeia (EP) Reference Standard

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Glycin suitable for electrophoresis, ≥99%

Sigma-Aldrich

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L-Glutaminsäure from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%

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L-Glutaminsäure

Richard A Felix et al.
Brain structure & function, 220(5), 2639-2652 (2014-06-30)
The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Bethany L Johnson-Kerner et al.
Human molecular genetics, 24(5), 1420-1431 (2014-11-16)
Giant axonal neuropathy (GAN) is a progressive neurodegenerative disease caused by autosomal recessive mutations in the GAN gene resulting in a loss of a ubiquitously expressed protein, gigaxonin. Gene replacement therapy is a promising strategy for treatment of the disease;
Suzanne L Grant et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 844(2), 278-282 (2006-08-08)
A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in
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