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Merck

G2878

Sigma-Aldrich

Glycocholsäure Hydrat

synthetic, ≥97% (HPLC)

Synonym(e):

Cholyl-glycin

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About This Item

Empirische Formel (Hill-System):
C26H43NO6 · xH2O
CAS-Nummer:
Molekulargewicht:
465.62 (anhydrous basis)
Beilstein:
2955826
MDL-Nummer:
UNSPSC-Code:
12161900
PubChem Substanz-ID:
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

Beschreibung

anionic

Assay

≥97% (HPLC)

Form

powder

Mol-Gew.

average mol wt 1000

Aggregatnummer

2.1

Methode(n)

enzyme immunoassay: suitable

CMC

7.1

Funktionelle Gruppe

amide

Versandbedingung

ambient

Lagertemp.

room temp

SMILES String

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

InChIKey

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

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Anwendung

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system.

Biochem./physiol. Wirkung

Gallensäure

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Gloves


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Examination of the Interaction of Chitosan and Oil-in-Water Emulsions Under Conditions Simulating the Digestive System Using Confocal Microscopy
Helgason, T., et al.
Journal of Aquatic Food Product Technology, 17, 216-233 (2008)
Konstantin Kazankov et al.
Hepatology (Baltimore, Md.), 60(2), 521-530 (2014-03-14)
Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C
Yazhou He et al.
PloS one, 9(3), e91202-e91202 (2014-03-14)
Association between the single nucleotide polymorphism rs3218536 (known as Arg188His) located in the X-ray repair cross complementing group 2 (XRCC2) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to
Raj S Bhopal et al.
The lancet. Diabetes & endocrinology, 2(3), 218-227 (2014-03-14)
The susceptibility to type 2 diabetes of people of south Asian descent is established, but there is little trial-based evidence for interventions to tackle this problem. We assessed a weight control and physical activity intervention in south Asian individuals in
Emanuel Christ et al.
The lancet. Diabetes & endocrinology, 1(2), 115-122 (2014-03-14)
Small benign insulinomas are hard to localise, leading to difficulties in planning of surgical interventions. We aimed to prospectively assess the insulinoma detection rate of single-photon emission CT in combination with CT (SPECT/CT) with a glucagon-like peptide-1 receptor avid radiotracer

Protokolle

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

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